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Axalbion Therapeutics Announces First Patient Dosed in Phase 2 Clinical Study in Chronic Cough with AX-8, a Novel TRPM8 Agonist; Proof-of-Concept Study with AX-8 Designed to Demonstrate Efficacy in Patients Suffering from Chronic Cough with Moderate-to-Severe Throat Discomfort

August 27, 2024

Manchester, UK and Mountain View, Calif, August 27, 2024 – Axalbion, a clinical-stage biopharmaceutical company focused on developing novel medicines to treat cough, announced that the first patient has been dosed in the second part of a Phase 2 proof-of-concept, randomized, placebo-controlled clinical study in chronic cough with AX-8, its lead compound. AX-8 is a potent and selective oral agonist of the transient receptor potential melastatin 8 (TRPM8) ion channel. The company has raised additional financing from existing and new investors to support the trial execution and Phase 3 planning.

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Press Release – Axalbion Presented Promising Phase 2 Clinical Data in Chronic Cough with AX-8, a Novel TRPM8 Agonist, in an Oral Presentation at the American Thoracic Society (ATS) 2023 International Conference

May 22, 2023

Proof-of-Concept Study Signals AX-8’s Potential in Chronic Cough Treatment, Especially in Patients with Moderate-to-Severe Throat Discomfort

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